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العنوان
Effect of beta-blockers on plasma levels of insulin and cortisone in normal and diabetic rats and their interactions with oral hypoglycaemic drugs
الناشر
Abdel Rahman Abd El Fattah Abd El Hady,
المؤلف
Abd El Hady , Abdel Rahman Abd El Fattah
هيئة الاعداد
باحث / Abdel Rahman Abd El Fattah Abd El Hady
مشرف / Effat Abd El-Ghany Haroun
مشرف / Gamal Farag El-Wahedi
مشرف / Mahmoud Abd El Moniem Abd El-Hamid
الموضوع
Diabetes mellitus. Prevalence & pysiopathgology.
تاريخ النشر
1987.
عدد الصفحات
116 p. ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأدوية (الطبية)
تاريخ الإجازة
1/1/1987
مكان الإجازة
جامعة المنصورة - كلية الطب - DEPARTMENT OF PHARMACOLOGY
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present work was conducted to study the effect of beta-adrenergic blockers propranolol and atenolol on the plasma insulin and cortisol level in the non-diabetics ana diabetic rats as well as the poss¬ible interaction, between these beta-blockers and the oral hypoglycaemics glibenclamide and glycodiazine with regard to their effect on the plasma glucose, plasma cholesterol, plasma cortisol and serum insulin levels. The data obtained in the study could be summarized as follows : 1- Glibenclamide produced highly significant reduction of the plasma glucose level , significanr reduction of the plasma cholesterol, significant elevation of the plasma cortisol and significant increase of the serum insulin level in the non-diabetic and alloxan diabetic rats in a dose 0.085 mg/kg orally dialy