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Abstract Diabetes mellitus is a chronic disorder of carbohydrate metablism which results from relative or absoulte irisulindeficiency.lt causes widespread patho¬logical changes in the human body. These changes are basically vascular and consist of two types ; non¬specific large blood vessel disease, and a specific small vessel disease or microangiopathy. These changes are generalized throughout the body, and indeed, the few histological studies of temporal bones of human diabetics and experimental animals, show changes in the small blood vessels of the stria vascularis, and the modiolus. The hearing loss associated with diabetes mellitus then may be a result of localised microangio¬pathy in the inner ear, but it might also be due to derangement in the metabolism of glucose, or a combina¬tion of the two. (Marshak, 1972). It has long been noticed that patients with diabetes mellitus are more susceptible to infection than non-diabetics, and, that infections of the diabetics takes more severe form. (Axline, 1982)* Twenty per cent of diabetics are first diagno¬sed because they nave persistent skin infections. (Alexander, 1982). |