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العنوان
The effect of high frequency positive pressure ventilation on hypoxic pulmonary vasoconstriction and pulmonary haemodynamics during one ­ lung ventilation /
المؤلف
El­-Tahan, Mohamed Mohamed Refaat Ali.
هيئة الاعداد
باحث / محمد محمد رفعت الطحان
مشرف / زينب محمود سنبل
مشرف / منى عبدالجليل حشيش
مشرف / نبيل عبدالرؤوف عبدالمجيد
مشرف / عمرو محمد ياسين
الموضوع
Thoracic. Anaesthesia. Ventilation. Pulmonary - Haemodynamics.
تاريخ النشر
2005.
عدد الصفحات
137 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنصورة - كلية الطب - Anaesthesia and Surgical Intensive Care Department
الفهرس
Only 14 pages are availabe for public view

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Abstract

High frequency positive pressure ventilation (HFPPV) is a technique of mechanical respiratory support based on the delivery of gases under conditions of constant flow and low pressure. This controlled prospective randomized study was carried out from 2002<U+2013> 2004 on thirty patients ASA physical status (SL (Band II, aged between 18 and 55 years scheduled for elective lung resection procedures in the Cardio<U+2013>Thoracic Unit­ Mansoura University Hospitals. General anaesthesia was induced by midazolam, fentanyl, and pipecuronium. Patients were randomly assigned to three groups: OLV group {n=10}: conventional one lung ventilation with tidal volume 10 ml.Kg­1, I: E ratio 1:2.5 and respiratory rate 12 <U+2013> 15 cpm. HFPPV group {n=10} HFPPV with tidal volume 3 ml.Kg­1, I: E ratio > 0.3 and respiratory rate 60 cpm. DLV group {n=10} HFPPV with tidal volume 3 ml.Kg­1, I: E ratio 1:3 and respiratory rate 60 cpm was applied to the non dependent lung with conventional one lung ventilation of the dependent lung. Haemodynamics and respiratory were recorded in the three studied groups. The use of HFPPV was associated with significant decrease in MPAP, PAOP, SVRI, PVRI, and SVI, LVSWI, RVSWI, REF and, EtCO2, airway pressures. In addition, it was associated with significant increase in RVEDVI, PaCO2, a <U+2013> Et CO2, SvO2, and continuous SvO2, CaO2, CvO2, and DO2. While, the use of DLV with conventional ventilation of the dependent lung with the application of HFPPV to the non<U+2013>dependent lung was associated with significant decrease in CI, SVI, SVRI, and PVRI, LVSWI, RVSWI, RVEF, and a <U+2013> Et CO2, a /A PO2, VO2, and O2ER . In addition, it was associated with significant increase in PAOP, RVEDVI, SvO2, continuous SvO2, and PvO2, CvO2, QS ­ QT, and DO2. Therefore, both techniques may be a valuable adjunct to ventilate patients with preexisting pulmonary disease who require lung retraction during thoracotomy requiring one­lung ventilation.