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العنوان
Nifedipene induced gingival hyperplasia histopathogical study /
المؤلف
Moustafa, Samir Mohamed.
هيئة الاعداد
باحث / Samir Mohamed Moustafa
مشرف / Laila M. A. Gadalla
مشرف / Khayria A. Elkordy
مشرف / Ebtessam M. Fathy
الموضوع
Histology, Pathological. Gingivitis. Gingival hyperplasia. Nifedipine.
تاريخ النشر
1994.
عدد الصفحات
49 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Periodontics
تاريخ الإجازة
1/1/1994
مكان الإجازة
جامعة المنصورة - كلية طب الأسنان - Department of Oral Medicine
الفهرس
Only 14 pages are availabe for public view

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Abstract

Uses drug Alnnifdben over a wide range in the treatment of angina and high blood pressure.
And sometimes accompanies its use in the gum tissue proliferation .
Examining these changes This study was conducted to examine the changes caused by Nifedipine on mice Basdhafah the gums to the relationship between the duration of give this property the highest dose and the severity of these changes and then examine these changes Balmikrscop the photosynthesis and studied study Hustobatolgah .
Was used in this experiment thirty fugitive white mature with an average weight of 200 grams VARs These mice were divided into groups :
Group A:
Consisting of ten mice not given any medication has been used.
Group B:
Consisting of 10 rats were given a dose equal to the highest human dose addressed of drug Alnnifdben .
Group C:
Consists of 10 mice also were given a dose equal to highest dose Anolha the rights for a period of three months, daily through a metal tube . After the end of the duration of the experiment mice were slaughtered .
The study was conducted Histologih after dye and then examined samples these samples Balmikrscop the scanner and recorded the results .
This study showed that the drug Alinvadben cause changes Mikrskobh the gum in a proliferation of mice with class ulcers and irregular proliferation of this class for which the medicine is given .
As found that of gum layer and spinal elongation stringed network , there is also an increase in the fiber Alkolajih and proliferation of fibroblasts .