الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Temporomandibular Joint disorders, particularly internal derangement (TMJ ID), present significant challenges in both diagnosis and treatment due to their complex nature. Traditional approaches such as splints, medications, and physical therapyhave shown limited success, prompting the exploration of alternative therapies. Prolotherapy has emerged as a promising intervention, aiming to stimulate tissue repair and alleviate symptoms. This study investigates the effectiveness of arthroscopic prolotherapy in improving pain levels and joint function in patients with TMJ internal derangement versus ringer solution.
This study focused on a specific subset of patients with (TMJ ID), particularly those with bilateral (DDwoR). The research aimed to compare radiographically and clinically the efficacy of surgical arthroscopy in the management of patients with (TMJ ID) using two different types of injection material Prolotherapy versus Ringer solution.
Thirty-three female patients were selected, along with the prespecified inclusion criteria. These patients were diagnosed with (TMJ ID) as class II or III according to Wilkes’s classification. Then recruited for the study six patients (twelve joints) who didn’t respond to the conservative treatment and proceeded to the arthroscopic surgery.
Significant improvements in (MIO) were observed postoperatively in both the prolotherapy and control groups (p < 0.05). Pain scores measured using the (VAS) decreased significantly in both groups, with a more notable reduction observed in the prolotherapy group (p < 0.05). Additionally, dietary scores showed significant improvement in both groups postoperatively, with no significant difference between the prolotherapy and control groups (p > 0.05). Similarly, quality of life scores exhibited significant enhancement in both groups (p < 0.05), with no statistically significant difference between them (p > 0.05). Moreover, MRI evaluations conducted at the 6-month
Discussion
postoperative mark revealed no significant change in disc morphology and position in both the prolotherapy and control groups.
Arthroscopic surgery combined with Prolotherapy showed significant improvements in (MIO), pain reduction, dietary habits, and quality of life. These findings suggest that Prolotherapy holds promise as an effective treatment option for TMJ ID, specifically for patients with DDwoR, warranting further research to solidify its role in TMJ ID management.