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العنوان
Troponin I Biomarker for Cardiac Affection in Patients with Androgentic Aloepcia/
المؤلف
Mohammed, Doaa Fawzy
هيئة الاعداد
باحث / دعاء فوزى محمد
مشرف / عادل على ابراهيم
مشرف / دعاء محمد الحباك
مشرف / شرين ابراهيم فرج
الموضوع
Dermatology Andrology Venerology
تاريخ النشر
2020
عدد الصفحات
94 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض المعدية
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة بنها - كلية طب بشري - الجهاز الهضمى
الفهرس
Only 14 pages are availabe for public view

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from 119

Abstract

Case control study was done for assessment of troponin I level of patients with AGA to detect if there is a role of troponin I as a cardiac biomarker for cardiac affection in the disease (AGA) pathogenesis and its associations and looking for a hidden cardiac problem.
The study was conducted on 75 participants; 50 patients suffering from Androgenetic alopecia, in addition to 25 control normal healthy persons (male and female), age and sex matched individuals as a control group.
The AGA group mean age was 34.4 years, they were 31 males (62%) and 19 females (38%). In addition to 25 healthy control group,
they were 11 males (44%) and 14 females (56%). there was no significant difference between both groups in smoking.
AGA group had significantly lower absolute value of GLS, higher troponin I when compared to control group (p<0.001). Troponin had better AUC than GLS which had better AUV than EF (AUC=0.920, 0.832, 0.696 respectively). Also, troponin I showed significant positive correlation with age, GLS, grades, as well as significant negative correlation with EF. Troponin I was considered as independent risk predictors for higher AGA grade