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العنوان
Changes in right ventricular free wall strain in patients with acute inferior myocardial infarction and patients with chronic coronary artery disease involving the right coronary artery /
المؤلف
Hakeem, David Tharwat.
هيئة الاعداد
باحث / David Tharwat Hakeem
مشرف / Mahmoud Ali Soliman
مشرف / Mohamed Yahia Abd- Alkhalk
مشرف / Mourad Beshay Mena
الموضوع
Cardiology. Coronary Heart Disease. Coronary Disease. Myocardial infarction.
تاريخ النشر
2024.
عدد الصفحات
107p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
17/8/2024
مكان الإجازة
جامعة المنوفية - كلية الطب - امراض القلب والاوعية الدموية
الفهرس
Only 14 pages are availabe for public view

from 116

from 116

Abstract

Myocardial infarction (MI) is a major cause of death and disability
worldwide. Coronary atherosclerosis is a chronic disease with stable and
unstable periods. During unstable periods with activated inflammation in
the vascular wall, patients may develop a MI.
MI may be a minor event in a lifelong chronic disease; it may even
go undetected, but it may also be a major catastrophic event leading to
sudden death or severe hemodynamic deterioration. Acute MI may be the
first manifestation of coronary artery disease, or it may occur repeatedly
in patients with established disease.
Right ventricular functions are affected in about one-third of the
patients by the inferior myocardial infarction (MI), as the most important
limitations, echocardiographic parameters evaluated with TDI are angledependent and influenced by myocardial tethering effect.
The involvement of the right ventricle (RV) has been defined as a
strong predictor of major complications and in-hospital mortality in
patients with acute inferior myocardial infarction (MI).
Despite the current large-scale use of primary percutaneous coronary
intervention (PCI), RV dysfunction after acute MI remains common and
associated with worse prognosis.
The Interest in evaluation of the right ventricular dimensions and
function has increased recently. With the rapid growing of the new
echocardiographic techniques and technology, there has been a corresponding increase in the ability to evaluate the RV, both qualitatively and quantitatively.
The main aim of the study:
The main aim of this study was to assess the RV mechanics to
detect changes in RV structure and function by speckle tracking
echocardiography in the patients with acute inferior MI and patients with
chronic coronary artery disease involving right coronary artery.
Methods:
This observational cohort study was conducted at Menoufia
University hospital. This study was conducted on 100 patients. All
patients were divided into 2 groups: group 1: patients with acute inferior
myocardial infarction and coronary angiography shows right coronary
lesion. group 2: patients with chronic coronary artery disease and
coronary angiography shows significant right coronary lesion.
The main results of the study showed that:
 We found no significant difference between the two studied groups
regarding age, sex and BMI.
 Hypertension was more prevalent comorbid in both groups.
Moreover, there is no significant difference was found between the
studied groups regarding studied comorbidities.
 There is no significant difference between the two studied groups
regarding heart rate, SBP, and DBP.
 There is no significant difference between the two groups
regarding EF. Mitral, tricuspid E/A ratio and estimated PASP.
 There is a significant difference between the two groups regarding
RV basal dimension, RV FAC, TAPSE, RVFWLS (basal, mid, and
apical) and RVGLS.
 RV FAC, TAPSE are significantly lower in acute inferior MI group
than CCS group (P value <0.001).
 RVFWLS, RVGLS are significantly lower (less negative value) in
acute inferior MI group than CCS group (P value 0.031) (P value
0.005) respectively.