الفهرس 
Primary Open Angle GlaucomaOnly 14 pages are availabe for public view
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Abstract
Background: Glaucoma is the most frequent cause of irreversible blindness worldwide. Detection of progression is crucial to prescribe appropriate treatment and reduce the likelihood of visual impairment associated with this disease.
Aim of the Work: The study will investigate how variations in optic disc perfusion correlate to various stages of POAG and hence, the potential role of OCTA in glaucoma severity classification and detection of progression.
Patients and Methods: This study is a cross-sectional observational study. Patients with primary open angle glaucoma (POAG) were recruited from the outpatient clinic at Ain Shams university hospitals from January 2023 till December 2023.
Result: OCTA was used to compare between the radial peripapillary capillary plexus (RPC) vessel density (VD) in 2 groups of POAG: eyes with mild glaucoma and eyes with moderate-severe glaucoma. Moreover, the correlation between visual field mean deviation (MD) and RPC VD was assessed. A statistically significant difference was found between the 2 study groups as regards the peripapillary VD (ppVD) as well as a highly significant positive correlation between RNFL thickness (RNFLT) and ppVD across the superior, inferior, nasal and temporal quadrants in both groups. Also, a highly significant positive correlation was found between visual field MD and each of RPC whole image VD (wiVD) and ppVD among both groups.
Conclusion: Peripapillary VD analysis exhibited diagnostic capabilities to differentiate between different stages of glaucoma severity and may prove to be a useful tool in monitoring POAG across stage and identifying glaucoma progression.