الفهرس 
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Abstract
Background: Hepatic focal lesions have been a common reason for consultation faced by gastroenterologists and hepatologists. It is important to consider not only malignant liver lesions, but also benign solid and cystic liver lesions.
Objective: to evaluate and confirm the role of magnetic resonant elastography in assessment of the hepatic focal lesions and differentiate benign from malignant hepatic focal lesions.
Patients and Methods: This is a cross sectional study included 30 patients with variety of focal lesions identified either by dynamic MRI or by histopathology.
Results: Our study showed that a cut off value of 4 Kpa had a 90% sensitivity, 85.7% specificity, 95% positive predictive value, 75% negative predictive value and accuracy 90 %.
Conclusion: MRE showed a great potential as a promising non invasive technique for quantitative evaluation of hepatic masses that could introduce more data useful in characterization of the focal lesions.
Keywords: Focal liver lesions, Magnetic resonance elastography,
INTRODUCTION
Focal liver lesions (FLL) are common in the general population and are frequently found during ultrasound examination either incidentally, in healthy subjects, in symptomatic patients and in patients with oncological history, during cancer staging or follow-up. Early detection and accurate characterization of FLLs are important for further management and treatment planning (Morana et al., 2010).
Imaging is an important decision-making tool in the diagnosis of focal liver lesions (FLLs), as it can accurately differentiate benign from malignant lesions in most of the cases. Most FLLs have a characteristic imaging aspect, however, follow-up and biopsy might be required (Cosmin et al., 2015).
With the widespread use of cross-sectional imaging techniques, the detection of focal liver lesions (FLLs) has become increasingly common. Many FLLs are incidental, and characterization with imaging is an effective means to reduce the need for invasive biopsies for histological confirmation (Hennedige et al., 2016).
Magnetic resonance elastography (MRE) is a non-invasive, magnetic resonance imaging (MRI)-based tool for quantitative assessments of hepatic tissue stiffness (Cho et al., 2020).
MR elastography, by evaluating the stiffness of a FLL, may provide a new quantitative parameter for characterizing FLLs. Preliminary experience with FLLs has demonstrated that MRE can differentiate malignant liver tumors from benign tumors and normal liver parenchyma (Venkatesh, 2014).
AIM OF THE WORK
The aim of this study is to assess the role of magnetic resonance Elastography (MRE) in differentiating benign from malignant hepatic focal lesions.