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العنوان
Relation between D-dimer level and coronary artery disease severity in patients with ST segment elevation myocardial infarction /
المؤلف
Aboshady, Mahmoud Zakaria Abd-Elsattar.
هيئة الاعداد
باحث / محمود زكريا عبد الستار أبوشادي
مشرف / غادة محمود سلطان
مشرف / تامر عزت غازي
الموضوع
Cardiology. Coronary heart disease. Myocardial infarction.
تاريخ النشر
2024.
عدد الصفحات
143 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
21/5/2024
مكان الإجازة
جامعة المنوفية - كلية الطب - أمراض القلب والأوعية الدموية
الفهرس
Only 14 pages are availabe for public view

from 153

from 153

Abstract

The anatomical SYNTAX (Synergy between percutaneous coronary
intervention with taxus and cardiac surgery) score is an angiographic scoring system
for assessing the complexity of coronary artery disease (CAD) while SYNTAX II
score included both anatomical and clinical variables
D-dimer is the end product of plasmin-mediated degradation of cross-linked
fibrin. Plasma concentrations of D-dimer, a marker of coagulation, are dependent on
fibrin generation and subsequent degradation by the endogenous fibrinolytic system.
Several studies have suggested that elevated D-dimer levels are associated
with adverse outcomes in patients hospitalized for myocardial infarction.
The current study was conducted to detect the relation between the serum
Level of D-dimer upon admission and the severity of coronary artery disease in
patients with ST segment elevation myocardial infarction.
The current study included 120 patients with ST segment elevation
myocardial infarction who were recruited from Cardiology Department, Menoufia
University Hospital and Banha Teaching Hospital.
in the current study, the mean SYNTAX II score was 27.82 ± 5.20 and there
were 57 cases (47.5%) with low SYNTAX II score (SYNTAX II score < 25) and 63
cases (52.5%) with High SYNTAX II score (SYNTAX II score ≥ 25).
The D-dimer level was statistically significantly higher in the cases with high SYNTAX II score as compared to the cases with low SYNTAX II score (p< 0.001).
The best cutoff point of D-dimer level to identify cases with high SYNTAX II
score was > 1.75 mg/L with 73.5% sensitivity and 64.5% specificity. The area under the curve was 0.701 and this value showed a statistically significant value (p = 0.001).