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العنوان
Effect of Growth Hormone Administration on ICSI Outcomes in Poor Ovarian Reserve :
المؤلف
Metawie, Ola Mohamed Abd Elhamid Abd Elmoneim
هيئة الاعداد
مشرف / Mohamed Hafez Mohamed Younis
مشرف / Waleed Elsayed Elrefaie
مشرف / Hesham Gaber Al-Inany
مناقش / muhammed muktar shaaban
الموضوع
Pregnancy.
تاريخ النشر
2024.
عدد الصفحات
119 P. ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Multidisciplinary
تاريخ الإجازة
13/2/2024
مكان الإجازة
جامعة بورسعيد - كلية الطب - Medicine
الفهرس
Only 14 pages are availabe for public view

from 119

from 119

Abstract

Total number of infertile ladies were 74 that were divided randomly into 2 groups, 37 in GH and control group. There was no statistical difference in their Age of infertility duration.
There was also no statistical difference in the AMH levels or AFC between the 2 groups. The GH group showed a non-statistically significant increase in the No. of mature follicles 4.46±1.82, compared with Control group 4.32±1.68. However, GH group showed a statistically significant change in E2 levels 1750.84±732.23 versus Control group 1293.78±574.96 with p Value 0.00386.
Results Showed that GH has a statistical difference in reduction of both duration of induction and dose of HMG used in the induction; Stimulation days 9.84±0.69 versus 11.1±0.74 in control group and HMG dose 4427.03± 309.48 versus 4998.65±331.76 for control group.
Total pregnancy rate in GH group was 29.73% for 18.92% in control group, this is a non-significant difference favoring for GH group.
When taking into account analyzing results between the pregnant and non-pregnant ladies. There was no statistical difference in Age or infertility duration. However, there was a statistical difference in the AMH levels higher in Pregnant group with 0.73±0.23 to 0.57±0.2 Control group, and the AFC was statistically higher in pregnant group 6.94±1.43 versus non pregnant group 5.36±1.73.
There was also statistically significant difference between pregnant and non-pregnant group in No. of mature follicles, which was higher in the pregnant group 5.5± 1.82 versus 4.04±1.57 in the non-pregnant group. Also, E2 levels showed a significant difference in the pregnant group versus the non-pregnant group 2023.72±755.23 and 1361±593.77 respectively.
There was no significant difference between pregnant and non-pregnant groups in the number of stimulation days and HMG dose.
By study the correlation between pregnancy and the above-mentioned factors, E2, AMH, AFC and number of Mature follicles were all significantly associated with pregnancy occurrence.