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العنوان
Cardiovascular Risk in Patients with Psoriasis ‎and Psoriatic Arthritis :
المؤلف
Abd El-Aziz, Yara Assem.
هيئة الاعداد
باحث / يارا عاصم عبد العزيز
مشرف / فاتن إسماعيل محمد
مشرف / فاطمة علي محمد
مشرف / حازم محمد علي
الموضوع
Psoriasis. Psoriasis - therapy.
تاريخ النشر
2024.
عدد الصفحات
205 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الروماتيزم
تاريخ الإجازة
15/4/2024
مكان الإجازة
جامعة المنيا - كلية الطب - أمراض الروماتيزم و التأهيل والطب الطبيعي
الفهرس
Only 14 pages are availabe for public view

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from 218

Abstract

Increased cardiovascular risk and subclinical atherosclerosis are linked to psoriatic ‎illness. For the assessment of subclinical atherosclerosis (SA), carotid ultrasonography ‎is helpful. Aim of the work: Determining the carotid intimal thickness (CIMT) in ‎individuals with psoriasis (PsO) who do not have cardiac disease. Patients and ‎methods: Thirty healthy sex and age-matched controls and thirty PsO cases were ‎included in this investigation. The carotid IMT was evaluated. SA was characterized by ‎the presence of plaque and/or IMT >0.9 mm. The Psoriasis Area and Severity Index ‎‎(PASI) was used to measure the disease activity in psoriasis. Body mass index, blood ‎pressure, waist circumference, and lipid profile estimation were performed on all ‎patients and controls. Results: PsO patients were 43.46 ± 13.94 years old on average, ‎with 43.3% of them being female. IMT was 0.47±0.06 mm in control and in PsO ‎‎(p<0.0001). In PsO, CIMT was substantially correlated with age (p<0.0001), disease ‎duration (p=0.001), and PASI (p=0.001). Conclusions: In psoriatic disease, ‎subclinical atherosclerosis has been connected to both disease activity and severity.‎