الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 92 |  |  |
| | | from | 92 | | |
Abstract
Nowadays Despite the advances in diagnosis and management of coronary artery disease (CAD) including acute coronary syndrome (ACS) it remains the leading¬ cause of death worldwide responsible for about 16% of all deaths approximately one-third of deaths worldwide. Risk factors for ACS are including Diabetes (DM), Hypertension (HTN) , Dyslipidemia, smoking, obesity and family history all of which plays a role in pathogenesis of IHD which is mainly coronary atherosclerosis.¬¬
Insulin resistance (IR), a feature of the metabolic syndrome (MetS), is highly correlated with a higher risk of MACE in addition to being a risk factor for CV disease. The key elements of MetS are high triglyceride (TG) and fasting plasma glucose (FPG) levels. Triglyceride-glucose (TyG) index, which combines TG and FPG levels, has recently been demonstrated to be a trustworthy indicator of IR in clinical practise.
The study aimed to assess the value of triglyceride glucose index in prediction of MACE in patients admitted with acute coronary syndrome.
This prospective study was conducted on 104 diabetic & non-diabetic patients admitted To CCU by Acute Coronary Syndrome in Sohag University Hospitals.
One hundred and four cases were included in our study. The age of studied patients ranged from 35 to 78 years with mean age (±SD) was 58.81± 9.82 years. The most common age group found was the age group >60 years in 42.3% cases, followed by age group 51-60 years in 38.5% cases then age group 41-50 years in 14.4% cases and age group 30-40 years in 4.8% cases. There was 72 (69.2%) males and 32 (30.8%) females
The results after following up of patients for 6 months showed incidence of heart failure in 9 patients, incidence of MI in 4 patients & incidence of CVS in 1 patient.
There was significant elevation in TYG index in cases with heart failure compared to cases without heart failure with index mean of 9.23 in HF cases. Also, cases with MI had significantly higher TYG index when compared to cases without MI with TYG index mean of 10.03 in MI cases.
In conclusion, the current study demonstrated that higher TyG index values represent a strong independent predictor and positive correlation relationship with increased risk of MACEs in ACS patients within 6 months.