الفهرس 
Definition and EpidemiologyOnly 14 pages are availabe for public view
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Abstract
Background: Infective endocarditis is defined as the infection of the endocardial lining of the heart, this encompasses the mural endocardium of heart valves as well as the endocardial covering of implanted materials such as prosthetic valves and intracardiac devices. Infective endocarditis (IEC) is a serious and potentially life-threatening condition if left untreated.
Objective: To identify demographics, risk profile and hospital outcome during hospital stay of young patients with infective endocarditis admitted to Ain Shams University Hospitals.
Patients and Methods: We developed a registry to describe patient demographics, risk factors, clinical features, and hospital outcomes for all cases of infective endocarditis diagnosed using modified Duke’s criteria referred to Ain Shams University in Egypt over a six-month period.
Results: Regarding the clinical manifestations, all patients presented with fever and nearly all had a cardiac murmur. Heart failure symptoms were reported mostly before admission yet we also had two cases that developed heart failure inpatient as a complication from valve vegetations. We also had a few patients that had immunological and vascular manifestations. Complications were experienced by the majority of our patients. Pulmonary embolism was the most common complication,, followed by acute kidney injury, sepsis, stroke, heart failure, and rarely splenic infarction and splenic abscess.
Conclusion: IE profile among Egyptian patients shows a rise in IVDU and a declining RHD trend. Staphylococcus aureus emerges as an important entity in NVE with or without IDU. While these findings should be confirmed by larger studies in multiple centers, our research emphasizes the importance of implementing effective policies to address the growing problem of IDU, ensuring adherence to infection-control practices, managing drug dependence, and appropriately selecting patients for valve surgery.