الفهرس 
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Abstract
Background: Reactive lesions (RLs) of the oral cavity are non-neoplastic lesions that are often a
response to persistent inflammation induced by different types of low-grade, chronic oral mucosal
irritations. They are tumor-like hyperplasia that are relatively common and have a clinical
appearance similar to neoplastic proliferations. This resemblance complicates the differential
diagnosis.
Aim: The purpose of this study was to evaluate the prevalence of reactive lesions diagnosed in
Cairo’s educational hospitals and institutions and to compare the results with findings in the literature.
Materials and Methods: Data of reactive lesions diagnosed between 2011 and 2020 were collected
from the files of the Cairo’s educational hospitals and institutions. Furthermore, stratification of age,
gender and site affection of each individual lesion will be performed.
Results: Reactive lesions of the oral cavity in the present study constituted 10% of all the 21420
registered oral and maxillofacial biopsies. A total of 2142 cases of RLs were collected and
reviewed. Of these, irritational fibroma was the common (40.7%) followed by pyogenic granuloma
(27%). The gingiva was the most common site, while the anterior part of maxilla was the most
frequently affected location. Females were commonly affected than males with ratio (1.8:1). The
highest occurrence of reactive lesions was found with patients in the third and fourth decades.
Conclusion: In this study we observed an obvious geographic variation in the relative frequencies
of various reactive lesions in Cairo governorate.
Keywords: Prevalence; Reactive lesions; Oral cavity; Epidemiology; Oral pathology; Cairo.