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العنوان
Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease/
المؤلف
Abdullah, Mai Hassan Mohammad.
هيئة الاعداد
مشرف / مصطفى محمود شاهين
مشرف / منى سعيد الحوشي
مشرف / هبة سعيد غراف
مناقش / أحمد يوسف شعبان
الموضوع
Chest Diseases.
تاريخ النشر
2023.
عدد الصفحات
62 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب الرئوي والالتهاب الرئوى
تاريخ الإجازة
28/12/2023
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Department of Chest Diseases
الفهرس
Only 14 pages are availabe for public view

from 76

from 76

Abstract

Cardiopulmonary exercise testing (CPET) proves to be of significant clinical utility when assessing individuals with chronic obstructive pulmonary disease (COPD) in various contexts. Patients with COPD are at an increased risk of cardiovascular comorbidities such as heart failure. Impaired cardiovascular function often has a significant impact on patients with COPD. Oxygen uptake and oxygen pulse provide objective and reproducible indices of cardiorespiratory fitness that can define prognosis and can be applied to the management of cardiovascular disease (CVD).
In current study we aimed to investigate the impact of COPD and coexisting heart failure on oxygen pulse and all CPET parameters. Additionally, we studied the association between peak O2P and most CPET variables.
The study included 50 patients with COPD who were divided into two groups: group I: COPD patients (n=25).group II: COPD patients with Left heart failure (n=25). All patients were subjected to forced spirometry, echocardiography and incremental CPET protocol conducted on an electronically braked cycle ergometer. Almost all patients were males (98%). Patients had insignificantly different smoking status, BMI, hemoglobin levels, GOLD stages and ABCD classification. Cardiovascular comorbidities were dominant in group II patients. As regards Echo parameters, LVEF% and stroke volume were statistically significantly lower in group II than group I.