الفهرس | Only 14 pages are availabe for public view |
Abstract Purpose: prediction of axillary lymph nodes status by detection of Intramammary lymph nodes (IMLNS) by radiological study. Materials and methods : The current prospective study was conducted at Mansoura University General Surgery Department (Department 7) to evaluate the prediction of ALN and IMNL status by preoperative imaging studies. A total of 54 women diagnosed with breast cancer were enrolled in our study. All patients received the standard preoperative assessment including history taking, clinical examination, and routine preoperative laboratory investigations. Radiological assessment was done via ultrasound, MRI, mammography, or combination of the previous modalities. IMLN and ALN status were recorded via radiological imaging. All patients underwent resection of their tumor, and histopathological analysis was done for all specimens with comment on ALN and IMLN status. Results: •For ALN assessment, radiology had a 89.5% sensitivity and 68.8% specificity when compared to the pathological examination, with an accuracy of 83.3%. •Age, affected side, molecular subtypes, BIRADS classification, and IMLN status did not pose a significant risk factor for ALN metastasis. However, all patients with positive ALN showed infiltration of the sentinel lymph node on preoperative imaging. •On the assessment of risk factors for IMLN cancer spread, no significant demographic, radiological, or clinical parameters were detected, apart from the radiological IMLN assessment, that showed an increased positivity in association with pathologically infiltrated LN (97% vs. 73.7% in free nodes, respectively). Conclusions : Based on our study findings, the incidence of axillary lymph nodes (ALN) and intramammary lymph nodes (IMLN) metastasis in breast cancer women is high. Preoperative imaging modalities have high sensitivity and diagnostic accuracy for the assessment of both lymph node groups. However, the specificity becomes very low in the assessment of IMLNs. Also, there is a pathological correlation with radiological results. Keywords : IMLN , ALN |