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العنوان
CHA2DS2-VASC score as a novel predictor for contrast associated nephropathy after percutaneous coronary intervention in acute coronary syndrome in Beni-suef Governorate - Egypt
المؤلف
Gomaa, Hassan Ramadan Abd Elazeem.
هيئة الاعداد
باحث / حسن رمضان عبد العظيم جمعة
مشرف / خالد السيد الحديدى
مشرف / هبة حمدي محمود
مشرف / ياسر أحمد عبد الهادى
مشرف / تامر محمد محمد
الموضوع
Acute Coronary Syndrome therapy. Percutaneous Coronary Intervention.
تاريخ النشر
2023.
عدد الصفحات
167 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب الباطني
الناشر
تاريخ الإجازة
5/11/2023
مكان الإجازة
جامعة بني سويف - كلية الطب - الباطنه العامة
الفهرس
Only 14 pages are availabe for public view

from 171

from 171

Abstract

Contrast induced nephropathy (CIN) occurs due to acute kidney injury caused by the contrast media and is a common cause of hospital-acquired acute renal failure.CIN is defined as a 25% increase in serum creatinine from the baseline value, or an absolute increase of at least 0.5 mg/dL (44.2 mmol/L), 48 - 72 hours after the administration of radiographic contrast media that is not attributable to other causes. Application of risk scoring systems can prognosticate the high risk patients for CIN after the exposure to contrast. Though there are various risk scoring systems available for prediction of CIN, the risk factor profile and their cumulative effect inacute coronary syndrome patients. In this study , three scores were done to early predict contrast induced nephropathyCHA2DS2 VASc , Mehran and GRACE scores were compared in total 648 patients with acute coronary syndrome.CHA2DS2=VASc showed the highest specificity prediction (100%) among the three studied scores, while GRACE score showed the highest sensitivity prediction (60%).The highest goodness of fit is for the combination of CHA2DS2-VASc and GRACE Score for CIN prediction (R2= 0.899, followed by prediction by CHA2DS2=VASc alone (R2= 893). so both scores can be used as independent predictors for CIN.