الفهرس 
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Abstract
The thyroid gland has a very important role in the body metabolism in general including the hematopoiesis. Blood disorders are frequently seen in patients with thyroid disorders because thyroid hormones have a very crucial role in the proliferation and the metabolism of red blood cells and all other blood elements. Thyroid hormones have a direct effect on the blood parameters by stimulating the precursors of the erythrocytes and indirectly by enhancing erythropoietin production Patients with thyroid abnormalities may have low iron levels which affect the hemoglobin levels, also they may have reduced levels of both folate and B12 which have been detected in up to 25% of patients, this eventually affects the blood parameters including the hemoglobin and the RBCs, other causes of anemia may include bone marrow suppression and other associated comorbid diseases. Anemia in patients with thyroid dysfunction is not only attributed to nutritional deficiency, but also due to reduction of thyroid hormones, this will result in lack of the stimulation of the erythrocyte precursors in the bone marrow, decrease in the oxygen supply to different tissues, and decrease in the erythropoietin level. Platelets are also affected in cases in thyroid dysfunction. Thrombocytopenia has been observed in hypothyroid patients. Mean platelet volume (MPV), plateletcreit (PCT), platelet distrbution width (PDW), platelet-large cell ratio (P-LCR) and platelet count are platelet parameters which asses platelet size, morphology and anisocytosis of circulating platelets and can reflect also platelet activity. Therefor the aim of this study was to study the effect of thyroid dysfunction on RBCS and Platelet indices. The present study was carried out on 100 patients and 50 healthy individuals of matched age and sex as controls. Patients were recruited from the wards and clinics of Internal Medicine Department, Tanta University Hospital, during the period from December 2021 to May 2022.