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Abstract 2-thioxodihydropyrimidine-4,6(1H,5H)-dione (1) was obtained by Adding sodium ethoxide solution, Thiourea and Diethyle malonate. The reaction mixture was kept reflux in (80%) yield. Scheme 1. Scheme 1 2,4,6-trichloropyrimidine (2) was obtained by putting 10 ml of Phospherous oxy chloride for each 1 gm of 1 and reflux it with stiring in (80%) yield scheme 2 Scheme 2 6-chloropyrimidine-2,4(1H,3H)-dione (3) was obtained by Adding of 2 to NaOH in 30 ml of water and reflux them in (50%) yield, scheme 3. |