Search In this Thesis
   Search In this Thesis  
العنوان
Track Structure Theory for Radial Dose Calculations and Its Biological /Effectiveness on Some Cells
المؤلف
El-Sheikh, Ahmed Salah Ahmed
هيئة الاعداد
باحث / أحمد صلاح أحمد الشيخ
مشرف / السيد محمود عوض
مناقش / محمود الغزالي محمد
مناقش / مجاهد إبراهيم الأبيض
الموضوع
Calculations of water target. Absorbed Dose Calculations
تاريخ النشر
2023
عدد الصفحات
134 P.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الفيزياء وعلم الفلك
تاريخ الإجازة
14/5/2023
مكان الإجازة
جامعة المنوفية - كلية العلوم - قسم الفيزياء
الفهرس
Only 14 pages are availabe for public view

from 156

from 156

Abstract

The track structure theory (TST), developed by Robert Katz and co-workers
over 50 years ago, gives the “full” predictions for both physical and biological
systems.
The work in this thesis is classified into 4 chapters as follows:
Chapter 1: Is an introduction to the interaction of charged particles with
matter and the track formation and ion track effects as a result of the emission of
secondary electrons (δ-rays) of enough energy was presented and the literature
models were given. These secondary electrons’ range-energy (R-E) relations were
gathered, and the corresponding radial dose distribution, RDD, formulas were given.
Chapter 2: Annular energy distribution per nm, AED is a concept introduced
to map the energy (dose) delivered by the secondary electron around the ion path in
the 2π directions. AED was calculated for a wide range of ions (185) of different
energies (from 1 to 200 MeV/n) forming 10 different equal LET groups (from LET=
4.2 to LET=1000 keV/μm) in a water target. Based on Katz (radial dose distribution)
and Butts-Katz & Tabata R-E relations, a simulation model was developed for radial
and annular energy distributions, Butts-Katz was used for the calculations and is
recommended for such study. Annular energy distribution, AED variation with the
annular width 𝑟 = 0.1 (𝑛𝑚) → 𝑟 = 𝑅𝑚𝑖𝑛(𝑛𝑚) for the different ions shows a clear
peak at a specific width called the maximum annular energy width, rMAEW, and
studied with the ion’s relative velocity, β2. The ratio of rMAEW of a given ion to the
VI
corresponding effective range, Reff was determined as 𝑟MAEW ≈ 63% Reff. Total
annular energy distribution, TAED is a new concept introduced, it integrates the
energy delivered by secondary electrons at all shells in the width between 𝑟 =
0.1 (𝑛𝑚) ⟶ 𝑟𝑀𝐴𝐸𝑊(𝑛𝑚) and it studied with the ion (Z*/ β)2