الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Several published studies investigated risk factors for cow milk protein allergy (CMPA), but the results have been conflicting. Therefore, the purpose of the current work is to identify the different risk factors associated with the development of CMPA as maternal, environmental and infants related risk factors.
This study was conducted among 141 CMPA patients and 142 healthy children.
All enrolled children were subjected to history taking stressing upon gestational age, type of delivery, feeding history during infancy: including duration and pattern of breast or formula feeding, type and time of introduction of complementary feeding, parents were asked about place of residence, number of siblings, maternal complication during pregnancy and family history of allergy, socioeconomic status and finally maternal dietary habits during pregnancy were evaluated by Perinatal food frequency questionnaire (PFFQ).
The following results were obtained:
1. The most common presenting symptom among CMPA was watery diarrhea in 105 cases (74.47%), and the least common symptom was angioedema in only 5 cases (3.55%).
2. The two group did not differ significantly regarding sex or maturity or birth weight.
3. There was significant association between neonatal intensive care unit (NICU) admission and incidence of CMPA p<0.001.
4. The percentage of CMPA cases (44.68%) who was admitted in NICU was significantly higher compared to healthy controls (23.24%) p =0.00014.
5. Significant higher proportion of CMPA cases belonged to the families with four (16.31%) and five children (6.38%).
6. Regarding the child rank among his siblings, highest percentage of CMPA cases was found in children ranked as the fourth (14.89%) and the fifth (4.96%) in their families.
7. No significant difference was found between different type feeding either exclusively BF, formula, or both. p=0.065.
8. The duratio