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Abstract
Hepatitis C virus infection (HCV) is a major and growing global health problem affecting about 170-200 million people worldwide. The prevalence varies markedly from one geographic area to another in which Egypt has the highest worldwide prevalence .HCV infection is one of the main causes of chronic liver disease worldwide,may complicated to chronic hepatitis, extensive fibrosis, and cirrhosis with or without hepatocellular carcinoma (HCC)