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Abstract
This study was done to compare the microbial colonization of flexible thermoplastic nylon (bre.flex) and heat cured acrylic resin in obturators restoring acquired maxillary defects. The experiment was carried out on six patients with acquired maxillary defect who are in need of definitive obturator. selected patients received metal framework prosthesis with heat cured acrylic resin bulb extending into the surgical site. At time of insertion a swab was obtained from the patients which represents the base line for situation I. Patients were followed after two and four weeks from wearing the obturator for microbiological evaluation and a swab was taken each time from the same place. In situation II, heat cured acrylic resin was replaced with flexible thermoplastic nylon (bre. flex) and a swab was obtained on the day of insertion as a base line for situation II. Patients were followed after two and four weeks from insertion of the replaced obturator for microbiological evaluation and a swab was taken each time from the same place