الفهرس 
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Abstract
AIM OF STUDY
The aim of the current study was:
1) Study the effect of sublethal doses of Malathion toxicity on experimentation on rats.
2) Investigate the protective role of ginger and green tea on hepatotoxicity and nephrotoxicity induced by Malathion in male rats.
3) Study of the effect by different doses Malathion on liver, kidney function, cholesterol and Fat derivatives in blood.
4) Identify the histopathological effect of Malathion on liver and kidney tissue.
5) Find out which treatments have the favorable biological effect.
ABSTRACT
The present study was designed to determine the modulating effect of ginger, green tea by different doses against adverse effects of Malathion. Rats were divided into eleven groups (5 rats /group). group one was used as a control, group two and three given malathion (50 mg/kg/day and 200mg/kg/day for four weeks), group four were given malathion (50 mg/kg/day and ginger 76.8 mg four weeks), group five were given malathion (200 mg/kg/day and ginger 76.8 mg four weeks), group six were given malathion (50 mg/kg/day and ginger 153.6 mg four weeks), group seven were given malathion (200 mg/kg/day and ginger 153.6 mg four weeks), group eight were given malathion (50 mg/kg/day and green tea 38.4 mg four weeks), group nine were given malathion (200 mg/kg/day and green tea 38.4 mg four weeks), group ten were given malathion (50 mg/kg/day and green tea 76.8 mg four weeks), group eight were given malathion (200 mg/kg/day and green tea 76.8 mg four weeks) respectively.
At the end of the fourth week, the malathion-treated group had significantly higher serum Alkaline Phosphatase (ALP), Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphates (ALP), urea, creatinine ,uric acid, low-density lipoprotein (LDL), Very low-density lipoprotein (VLDL), Triglycerides (TG) and Cholesterol (CHOL) levels than the control group and the malathion-treated group had significantly lower Body Weight Gain (BWG),food intake(FI) and food efficiency ratio (FER), High-density lipoprotein (HDL) levels than the control group .
Histopathological studies revealed that the malathion-treated, Malathion plus Ginger and Malathion plus green tea treated groups exhibited histopathological changes in liver and kidney tissues, although some pathological features were only observed in the malathion-treated group. Thus, Ginger and green tea can reduce Malathion hepatotoxicity and nephrptoxicity