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العنوان
Study of executive functions and white matter integrity using diffusion tensor imaging in childhood absence epilepsy/
المؤلف
Salama, Samy Yousry Eisa .
هيئة الاعداد
مشرف / حورية محمد سعد الله
مشرف / محمد إيهاب سامي رضا
مشرف / هبة عصام أبو الوفا
مشرف / ميرفت حامد عبد الرؤف المسدي
الموضوع
Neuropsychiatry.
تاريخ النشر
2023.
عدد الصفحات
72 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب (متفرقات)
تاريخ الإجازة
15/5/2023
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Department of Neuropsychiatry
الفهرس
Only 14 pages are availabe for public view

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from 86

Abstract

CAE is an epileptic syndrome that responds well to treatment. It is known to be one of the IGE in accordance with the current classification of the ILAE. Although CAE has usually been considered a benign disorder, many of the affected children suffer neurocognitive deficits. They have interictal problems with attention and executive functions, which persist even with proper seizure control. So in the present study, we aimed to assess the executive functions and white matter integrity using DTI in school- age children with CAE and to find possible correlation between clinical epilepsy variables, executive functions and white matter abnormalities detected by DTI.
To achieve these aims, a cross-sectional study was conducted at the epilepsy center at the Neurology department, Alexandria University Hospitals in Egypt on Thirty patients with CAE and fifteen healthy control subjects with normal neurological examination, MRI and matching in (age, gender, socioeconomic status and educational level) to the patients’ group .The patients’ group was subdivided into 2 subgroups: fifteen school- age children with CAE and on antiepileptic drugs (AEDs) for more than one year (AED-treated subgroup) labeled as group I and fifteen school-age children with drug -naïve newly diagnosed CAE (drug- naïve subgroup) labeled as group II. The control group labeled as group III.