الفهرس 
Title : Evaluation of the antimicrobial effect of 980nm Diode laser treated pure-platelet rich plasma and pureplatelet rich fibrin on the periodontal pocket pathogens -in vitro study
AbstractOnly 14 pages are availabe for public view
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Abstract
Background: Platelet concentrates have been extensively used in a variety of medical fields to promote soft and hard tissue regeneration.Other than releasing a pool of GFs upon activation, platelets also have many features that indicate their role in the anti-infective host defense.Objectives: This study aims to compare the effect of low intensity laser on in vitro bacterial growth and antimicrobial properties of platelets rich plasma (PRP) and platelets rich fibrin (PRF) against oral cavity microorganisms such as S.aureus, E.faecalis, andS.mutan.Methodology: In vitro antimicrobial activity was determined by broth mico-dilution method, the assay was applied to Staph.aureus, E.faecalis, andStrept.mutans to calculate minimum inhibitory concentration (MIC) of Radiated PRP and PRF in whole blood with 980nm wavelength diode laser with energy density of 1.5j/cm2 for 3second, and non-radiated PRP and PRF. Results: In vitro antimicrobial activity of platelet rich plasma (PRP) and platelets rich fibrin (PRF) were significantly increased after radiation, and the antimicrobial effect of PRP was higher than that of PRF. Conclusion: The most bacterial reduction ratio presented in case where the bacterial isolates treated with radiated PRP. Emerging PRP and low level laser seems to be a promising alternative tool besides antibiotic treatment