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Abstract
Objective: To study the correlation between fetal lung volumes (FLVs), determined by three-dimensional ultrasound and virtual organ computer-aided analysis software (VOCAL), with neonatal respiratory outcomes. Study Design: prospective observational study. Setting: Obstetrics and Gynecology casualty department, Kasr El-Aini hospital, Cairo University, Egypt in the period from June 2014 to December 2014. Methodology: One hundred healthy women with singleton pregnancies presented in the 1st stage of labour were included in the study, divided into two groups; group A (n: 50 - women pregnant ± 34-37 weeks) & group B (n: 50 - women pregnant ± 37+1-40 weeks). A 3D volume model of the right fetal lung is generated & lung volume is calculated using VOCAL software. After child birth, neonatal respiratory functions were assessed using APGAR score together with occurrence of RDS and the further need for NICU admission. Results: In group A, FLV was positively correlated with gestational age, while it was negatively correlated with APGAR score, RDS & NICU admission. In group B, FLV was positively correlated with gestational age, while there was no statistical correlation between FLV & APGAR score, RDS, NICU admission. Conclusion: 3D FLV using VOCAL technique might be an accurate non- invasive predictor for fetal lung maturity particularly among preterm fetuses