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Abstract Purpose: to find out the effect of moderate aerobic exercise (acute and chronic) on coagulation profile for patients with type 2 diabetes mellitus. Methods: Forty patients of both genders, aged 40-50 years, suffer from type 2 D.M. were divided into two equal groups. group (A) received aerobic exercise for twelve weeks (3days per week) .group (B) received aerobic exercises for only one session in form of treadmill. Results: group (A), there was no statistical significant difference in prothrombin time, prothrombin activity, platelets count and INR after application of 12 weeks of regular moderate aerobic exercise when compared with the corresponding mean value before initiation of treatment. group (B), Acute aerobic exercise (only one session) showed no statistical significant difference in prothrombin time |