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Abstract
liver diseases represent significant number of population all over the world, an easy research methodology should be available to enlarge the options available, but the ease of research must not be on the expense of accuracy and precision, the current study utilized a methodology in which a great results could be obtained easily in accurate and precise way, PCLS model representing a tunnel between the in vivo sophisticated methods and the in vitro methods. Finding a highly effective research methodology is of great importance so as to accelerate the rate of enhancing human life against the fast growing disease attacks