الفهرس يوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Exposure to waste anesthetic gases carries significant health hazards; genotoxicity is an identified risk among others. This study was conducted to evaluate the possible genotoxic effects of waste anesthetic gases on exposed medical personnel working in Kasr Al Aini hospitals. Sister chromatid exchanges (SCE) and micronucleus tests (MN) were performed on 31 exposed and 32 non exposed subjects. Both SCE and MN showed significant difference between the two groups. SCE was correlated to MN in the exposed group. SCE and MN significantly increased with age and duration of work. However no effect of smoking or sex was observed. Comet assay was performed on 32 operation room (OR) personnel and 35 non exposed. The study revealed significantly increased comet parameters (mean comet tail length and moment) in peripheral blood lymphocytes of OR personnel in comparison with control individuals