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Abstract
Background and Objective:Neurological complications (NC) affects up to one third of patients after Liver transplantation (LT). The aim of this study is to assess the incidence, risk factors and clinical presentation of NC after liver transplantation in patients who underwent living donor liver transplantation (LDLT) in Egypt. Methods: Between November 2011 and December 2013, 149 patients from diffrent centers were observed for one month after LDLT and evaluated by full general and neurological examination, assessment of encephalopathy by West Haven classification, full laboratory investigations including drug levels, and brain CT and/or MRI . Results: 46 patients (30.9%) developed neurological complications 30 of which (20.1%) developed side effects related to Tacrolimus (FK-506) and 2 patients (1.3%) developed side effects related to cyclosporine. The most common neurological complications were Encephalopathy (14.1%) while the least were both Central pontine myelinolysis and Meningoencephalitis (0.7%)