الفهرس | Only 14 pages are availabe for public view |
Abstract : In Meniere’s disease, distention of the structures filled with endolymph occurs. The cochlear duct, saccule, utricle or ampulla contain endolymph, and a change in volume of these structures are tightly correlated with the symptoms of Meniere’s disease (MD). It is known that episodic vertigo, fluctuating sensorineural hearing loss, tinnitus, and/or aural fullness are the four typical clinical symptoms of this disease. However, the clinical features that the patient presents are always quite atypical, especially in an early stage. Objective: to asses the role of MRI in diagnosis of Meniere’s disease Methods: 20 adult patients diagnosed as Meniere’s disease (11 males and 9 females) were examined by c-VEMP and MRI. Results: the affected ear showed a significant delay in latency of P13&N23 in cVEMP and a significantly decreased in N1-P1amplitude compared to the non-affected ears. MRI results: it was divided into Quantitative and Qualitative: Quantitative mothod: 6 out of 20 cases (30%) were positive for Meniere and 4 of them were positive with other pathologies 14 out of 20 cases (70%) were Negative for Meniere and 4 of them were negative with other pathologies. Other pathologies were either high arched jugular bulb or AICA vascular looping which causes Tinnitus in the affected side. Qualitative mothod: According to SURI grading (sacculo utricular ratio index) Attye et al., (2017) it was done on 7 of the 20 cases. Results were found 6 positive cases (85.7%) were graded as SURI Grade 1 1 out of 14 negative cases (14.3%) were graded SURI Grade 0 The specificity and sensitivity of the SURI were 100% and 30% respectively in our results Conclusions: cVEMP is a reliable objective method in evaluating the saccular dysfunction in MD patients. For MRI it states the degree of saccular morphology, cochlear hydrops and vestibular hydrops. MRI is a reliable objective method in confirming the diagnosis of Meniere`s disease as it states the degree of saccular morphology |