الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by auto antibodies directed against nuclear antigens and causing a variety of clinical and laboratory abnormalities. SLE can involve multiple organs, causing significant morbidity and mortality in adults, adolescents, and children.The kidney is the most commonly involved visceral organ in SLE , however only approximately 50% of patients with SLE develop clinically evident renal disease, biopsy studies demonstrate some degree of renal involvement in most patients.Lupus nephritis is a major cause of morbidity and mortality in systemic lupus patients so looking for the clinical , laboratory data and histopathology of them on admission help in making the best plan of management and subsequently improvement of the outcome. The 2012 American College of Rheumatology (ACR) guidelines for lupus nephritis recommend renal biopsy for all cases of active, previously untreated lupus nephritis, unless contraindicated.Aim of this study is to Elucidate the demographic criteria of the patients, asses the clinical characteristics of patients on admission, obtain a detailed laboratory data of the patients belong the activity of the diseases and/or its complication and detect the histopathology characteristics of the kidney tissue and determine the disease activity and degree of chronicity .