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Abstract -Subthalamotomy, pallidotomy and thalamotomy can effectively improve parkinsonian symptoms. They are considered the best available options for the developing countries which cannot afford costs and programming of deep brain stimulation. -Subthalamotomy and pallidotomy have near results in treatment of PD. But subthalamotomy has significant better outcomes regarding to body bradykinesia, postural instability and gait disability. -Both subthalamotomy and pallidotomy are preferable to thalamotomy as they adequately suppress bradykinesia and rigidity in addition to their adequate effect on tremor. -Subthalamotomy allows levodopa dosage reduction. -Pallidotomy is advised if the main complain of patient is dyskinesia. -Thalamotomy can be done in tremor predominant PD only. -We need a large study to confirm safety of subthalamotomy, pallidotomy and thalamotomy. -We need another larger study to compare between outcomes of lesioning surgeries and deep brain stimulation in treatment of PD. |