الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Osteoarthritis (OA) is a chronic disease of the joints that typically affects elderly individuals and causes pain and disability. Articular cartilage and underlying bone are damaged by the degenerative joint condition osteoarthritis (OA), Its multifactorial etiopathogenesis is characterised by subchondral bone remodelling, joint inflammation, osteophyte generation, and progressive loss of articular cartilage. Despite being a ”tear and wear” disease, complicated interactions between metabolic, genetic, biochemical, and mechanical elements are also crucial to the development of the illness.
The standard course of treatment includes NSAIDs, acetaminophen, physical exercise, weight management, and aquatic therapy. When these measures fail, total knee arthroplasty may be recommended.
After total knee replacement, there are various described approaches to treat postoperative pain. The current regional anaesthesia methods utilised following TKR concentrate on more peripheral, motor-sparing blocks to allow for early ambulation and high-quality pain control.
The aim of this study was to compare between ultrasound guided Adductor canal block with genicular nerve block versus ultrasound guided adductor canal block alone for providing analgesia after total knee replacement.
The present study was carried out in Hadara University Hospital, on 30 patients of both sex aged above 40 years old belonging to ASA class I or II scheduled for unilateral primary total knee arthroplasty divided into two groups using closed envelope method:
• group adductor canal block (A): 15 patients received adductor canal block alone.
• group adductor canal block and genicular nerve block (AG): 15 patients received adductor canal block and genicular nerve block.
This study was a prospective randomised single blinded comparative study.
The sample size was approved to be sufficient by the Department of Statistics, Medical Research Institute, University of A