الفهرس يوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Four Sterculia species (Sterculia alata Roxb., Sterculia diversifolia G. Don, Sterculia platanifolia L.f. and Sterculia foetida L.) grown in Egypt were selected for studying from a pharmacognostical point of view. On the basis of some morphological features, these species were reclassified under different genera and revised as Pterygota alata (Roxb.) R. Br., Brachychiton populneus (Schott & Endl.) R. Br. and Firmiana simplex (L.) W. Wight, respectively. Sterculia foetida L. remained belonging to genus Sterculia. In the present study, genetic, botanical, phytochemical and biological studies were performed in order to find the infrageneric relationships among the four taxa. Genetic analysis through DNA (RAPD-PCR fingerprinting of the fresh leaves) and protein (SDS-PAGE analysis of the seeds) profilings showed great genetic variations between the studied species. The botanical study included the investigation of macromorphological (vegetative and floral morphology) and micromorphological (leaves) characters. Macromorphological characters displayed considerable variation in leaves, inflorescence, fruits and seeds, while the micromorphological ones showed various similarities among the four species. Non-glandular and glandular trichomes were the main differentiating characters among the four species. The phytochemical investigation included proximate analysis, phytochemical screening, chromatographic investigation, isolation and structural elucidation of the flavonoid compounds, as well as qualitative and quantitative estimations of total flavonoid and phenolic contents by HPLC. from aqueous methanol extracts of leaves and stems of P. alata and B. populneus, 37 flavonoidal compounds (8 of which are common in both plants) in addition to 4 non-alkaloidal nitrogenous bases (from P. alata only) were isolated and identified using chromatographic and spectroscopic techniques. Their structures were established on the basis of detailed chemical degradation (acid hydrolysis, ferric chloride degradation and alkaline hydrolysis) as well as spectral analyses (UV, NMR and EIMS)