الفهرس 
Reminerlization of white spot lesions by Casein phosphopeptide amorphous calcium phosphate Tricalcium phosphate and Fluoride with different application times An in vitro study
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Abstract
The aim of this study was to evaluate the effect of casein phosphopeptide amorphous calcium phosphate, tricalcium phosphate versus fluoride with different application times on remineralization of enamel using microhardness test. A total number of 60 specimens from 30 sound molar teeth. The microhardness of all teeth was measured usingVicker{u2019}s micro-hardness machine. the specimens were soaked in a demineralizing solution for 72 hours to induce white spot lesions. where A1 represent specimens treated with CPP-ACP varnish (MI varnish ); A2 specimens treated with TCP varnish (Clinpro white varnish ); and A3 specimens treated with fluoride varnish (durashield varnish). Each group were divided into two subgroups according to times of application (T), where (T1) once application for two weeks and (T2) twice application for two weeks. Followed by the pH-cycling for two weeks. Showed that none of the tested varnishes able to restore microhardness baseline value. After single application, the CPP-ACP recorded high microhardness value with 71.93% percent of recovery However after double application TCP recorded 72.15% recovery. All tested remineralizing varnishes have the ability to remineralize enamel white spot lesion, Incorporation of CPP-ACP, TCP with fluoride varnishes increases the remineralization potentiality of these varnishes