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العنوان
Immunohistochemical expression of foxm1 in colorectal carcinoma /
الناشر
Mohamed Ahmed Ahmed Hussien ,
المؤلف
Mohamed Ahmed Ahmed Hussien
هيئة الاعداد
باحث / Mohamed Ahmed Ahmed Hussien
مشرف / Samira Abdalah Mahmoud
مشرف / Ahmed Abdelmoneim Soliman
مشرف / Lubna Omar Elfarouk Abdelsalam
تاريخ النشر
2016
عدد الصفحات
146 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء الحيوية (الطبية)
تاريخ الإجازة
9/3/2016
مكان الإجازة
جامعة القاهرة - كلية الطب - PATHOLOGY
الفهرس
Only 14 pages are availabe for public view

from 161

from 161

Abstract

Globally colorectal carcinoma is the third most common cancer in the world. There is an urgent need to identify markers of CRC progression and invasiveness to be more accurate in predicting prognosis. This study aimed to assess immunohistochemical expression of FoxM1 in CRC and correlation of this expression with the clinico-pathological aspects of the tumor using 32 formalin fixed paraffin embedded tumor tissue. FoxM1 high expression was significantly correlated with tumor stage, nodal metastasis and site of tumor (p-value 0.024, 0.033 and 0.03 respectively),while was not correlated with age, sex, size, histologic grade and type (p- value > 0.05). Our results are favoring that FoxM1 high expression can be correlated with CRC progression