الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Acute upper gastrointestinal bleeding is one of the most life threatening complication in patients with liver cirrhosis. Varices either esophageal or gastric are the most common causes of UGIB in those cirrhotic portal hypertensive patients. But there are another causes aside varices for UGIB in those patients (Goncalves et al., 2016). The aim of our work is to estimate the non variceal causes and to monitor the clinical outcome of acute UGIB in cirrhotic patients admitted to Zagazig University Hospital Tropical Medicine Intensive Care Unit.
Patients and methods: In this cross sectional analytical study, one hundred and seventy nine patients with liver cirrhosis diagnosed by combination of clinical, radiological and laboratory evidence, admitted to ICU and emergency endoscopy unit with acute upper GI bleeding. All patients were subjected to detailed history taking, thorough clinical examination, laboratory investigations including; CBC, coagulation profile and liver and renal functions and abdominal ultrasonography. The severity of liver disease was assessed using Child-Turcotte-Pugh classification and risk stratification of patients was applied using Glasgow-Blatchford score.After initial resuscitation was made to correct haemodynamic shock and coagulation profile through intravenous fluid, packed RBCs and plasma transfusion, the pre-endoscopic medications were given to the patients including; proton pump inhibitors, prokinetics, prophylactic antibiotics and vasoactive agents.