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Abstract nRBCs are immature erythrocytes whose production is thought to be driven primarily by the interplay of hypoxia and EPO synthesis or inflammatory mediators of sepsis. nRBCs count has been known to be closely associated with BPD, IVH, NEC and death. Increased rates of adverse neonatal outcomes, such as cerebral white matter injury, NEC and PDA, have also been associated with elevated nRBCs in preterm infants. Therefore nRBCs are promising as markers of severe illness and could be useful for monitoring critically ill infants patients beyond the first days of life. In this work we tried to evaluate increased nRBCs count as a predictor of EOS and to compare it in some critically ill neonates. This study conducted on 94 newborn infants, presented to NICU of Menoufia University and Shebin El-Kom Teaching Hospital in the period from november 2021 to november 2022 The Patients were divided into two groups: 62 neonates have any detected nRBCs, their weight ranged between (1.1 – 3.9) Kg. They were 32 males and 30 females. And 32 neonates have not detected nRBCs, their weight ranged between (1.2 – 3.5) Kg. They were 16 males and 16 females. They had clinical presentation of early critically ill. All studied group were subjected to the following: Prenatal, natal and postnatal history, Neonatal physical examination, Laboratory investigations included: Complete blood count, Blood was collected in a purpletopped EDTA tube for a complete cell blood count and nRBCs count, Estimation of CRP, Blood culture and Arterial blood gases samples. We used manual microscopy to count the nRBCs for which a DROP of blood was smeared over a glass slide and stained by the Wright method. |