الفهرس 
Common asthma triggers includeOnly 14 pages are availabe for public view
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Abstract
Asthma is a multifaceted disease marked by recurrent airway inflammation. There are limited studies on the effect of acute bronchial asthma on left ventricular functions. Objectives: The aim of the present study is to evaluate the ability of 2D‐STE (Speckle Tracking Echocardiography) and 3D-STE and TDI (Tissue Doppler Imaging) besides TDI and the conventional echocardiography for up detecting left ventricular diastolic and systolic cardiac dysfunction in children with mild, moderate and severe bronchial asthma. Patients and Methods: Forty-five children with asthma according to GINA (2020) definition of asthma aged between 5 and 18 years, and Fifteen control children with comparable age and sex distribution were included in the study. All children will be subjected to Complete blood picture, Total IgE, and spirometry test FEV1, FVC, FEV1/FVC. Echocardiographic parameters in the form of M-mode, Pulsed-wave tissue Doppler imaging, 2D and ED speckle tracking echocardiography. Results: There was no significant difference between asthmatic children and control as regard 2D SR but there was highly significant difference in TDI and 3DS in asthmatic children as compared with control ones, where in TDI there was highly significant increase in E/A and MPI in asthmatic patients than control. There was a statistically significant positive correlation between LS 2D (longitudinal, circumferential, area and radial), Tissue Doppler Imaging Systolic function (STDI), three-dimensional area strain (A 3D), three-dimensional radial strain (R 3D), two-dimensional systolic function (S 2D), Early diastolic two-dimensional (E 2D) parameters XVI Conclusion: In the present study we noted that asthmatic children are susceptible to variable degree of ventricular dysfunction which can be detected by 2D‐STE and 3D-STE and TDI of Echocardiography.