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العنوان
Clinicopathological study of steroid resistant nephrotic syndrome in children attending Alexandria university children’s hospital/
المؤلف
Elbeltagi, Youmna Ahmed Hassan.
هيئة الاعداد
باحث / يمنه أحمد حسن البلتاجي
مناقش / محمود محي الدين القرش
مناقش / محمد علاء الدين حسن ثابت
مشرف / نانسى عبد السلام كامل
الموضوع
Pediatrics.
تاريخ النشر
2023.
عدد الصفحات
37 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
28/1/2023
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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from 49

Abstract

Nephrotic syndrome is a disease with favorable outcome in most cases. Failure to respond to steroids is one of the most important predictors of clinical outcome. We performed a retrospective study on 51 idiopathic SRNS cases presenting between January 2011 and June 2021 by retrieving data from their clinic files. Cases with secondary causes of NS or suspected genetic cause were excluded from this study. Patients’ demographic data, clinical and laboratory findings at the time of presentation, complications occurring during the course of treatment, immunosuppressants used along with steroids and outcome at last follow up were recorded. The mean duration of follow up was 5.67 ± 3.07 years, with a minimum duration of follow up of 13.5 months for all patients and a maximum duration of follow up of 11.73 years.
Our results showed that there was male predominance (2.9:1), the mean age at first presentation was 4.53 ± 3.03 years, persistent hematuria and systemic hypertension were found in 25.5% and 54.9% respectively. Transient reduction of estimated GFR occured in some of the cases due to associated hypovolemia. Some cases showed elevated hemoglobin (9.8%). Elevated platelets count was found in 61% of the patients.