الفهرس | Only 14 pages are availabe for public view |
Abstract Fluconazole (FLZ) is a broad spectrum antifungal agent. It has a broad spectrum activity and inhibits nearly all clinically relevant dermatophytes, yeasts, and moulds. Thus, Fluconazole has proven useful for a wide variety of superficial dermatoses. Fluconazole inhibit cytochrome P450 that converts lanosterol to ergosterol, and is required in fungal cell membrane synthesis The aim of the work in this thesis was to formulate Fluconazole in certain topical dosage forms suitable for the patient to treat different skin fungal diseases. The work in this thesis is divided into four chapters namely: >Chapter I: Formulation and Evaluation of Fluconazole in Different Hydrogels Dosage Forms. >Chapter II: Formulation and Evaluation of Fluconazole in Different Emulgels Dosage Forms. >Chapter III: Formulation and Evaluation of Fluconazole in Different Microemulsion based hydrogels Dosage Forms. >Chapter IV: Antifungal activity of Different selected prepared Fluconazole Dosage Forms |