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Abstract Petroleum refineries are major emitters of volatile organic compounds mainly benzene, toluene, ethyl benzene, and xylene (BTEX). Long term exposure to BTEX carries the risk of oxidative stress, through the production of ROS that may consume antioxidants including antioxidant enzymes and their cofactors like antioxidant trace metals. This study aimed to assess oxidative stress in petroleum refinery workers exposed to BTEX. Aim of the work Assessment of oxidative stress among petroleum workers exposed to BTEX. Type of the study A cross sectional comparative approach was adopted. Subjects and methods Subjects Forty workers exposed to BTEX in a petroleum refinery together with an equal number of unexposed workers were enrolled in this study after fulfilling inclusion and exclusion criteria and giving an informed written consent. Methods The following tools were employed for data collection. These included: 1. A questionnaire to collect the socio-demographic, occupational and medical data from all workers. 2. Detect the BTEX exposure urinary biomarkers (S-phenyl mercapturic acid, hippuric acid, mandelic acid, methyl hippuric acid). |