الفهرس 
Title : Multi-variant analysis of different prognostic factors affecting the response to transarterial chemoembolization
AbstractOnly 14 pages are availabe for public view
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Abstract
Objectives: To identify clinical and imaging features associated with tumor response after one session of transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma.Material and Methods: In this prospective cohort, 150 patients who received one TACE from July 2018 to June 2019 were studied. Imaging response was evaluated according to the modified Response Evaluation Criteria in Solid Tumors (mRECIST). Age, gender, etiology of cirrhosis, clinicopathological features: tumor location, nodule size, segmental portal vein invasion, hypervascularisation on CT/MRI scans, Eastern Cooperative Oncology group (ECOG) performance status, Child-Pugh stage; biochemical indexes: while blood cell, hemoglobin, platelet, albumin (ALB), total bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, INR, alpha-fetoprotein (AFP) levels were analyzed.Results: After one session of TACE treatment, CR was observed in observed in 18.7 % of the 150 patients. As to CR achievement tumor size < 5 cm and supereselective approach are associated with greater possibility for CR achievement, while high AST and ALT >50 IU/L could predict less possibility for CR achievement. While ORR was observed in observed in 77.3 % of the 150 patients. As to ORR achievement, univariate analysis illuminated that tumor size <5 cm, tumor hypervascularity and supereselective approach are associated with greater possibility for ORR achievement, while segmental PV invasion and high ALT >50 IU/L could predict less possibility for ORR achievemen