الفهرس 
Urinary N-Acetyl-?-D glucosaminidase (uNAG) levels as an early marker for diabetic nephropathy in children with type1 diabetes
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Abstract
Background: Diabetic nephropathy is a major cause of morbidity and mortality among young adults with type 1 diabetes. Clinical management and therapeutic intervention from early stage of DN is of great importance to prevent progression to end-stage renal disease. Aim of work : The aim of our study is to evaluate the level of urinary N-acetyl-beta-D-glucosaminidase (NAG) in urine as a marker of tubulointerstitial damage in children with type 1 diabetes in relation with the level of microalbuminuria and renal function in order to explore the potential role of NAG as an early predictor for the progression of nephropathy in type 1 diabetic patients. Methods: A cross-sectional study done on 60 patients with type 1 diabetes mellitus at Diabetic Endocrine Metabolic Unit (DEMPU). They were categorized into two groups (normoalbuminuria and microalbuminuria) and 30 healthy controls recruited from general pediatric clinics. uNAG level was measured in the urine samples of all 90 patients