الفهرس 
Radiation modification of some natural polymers and its possible biomedical applications
ABSTRACTOnly 14 pages are availabe for public view
 |  | from | 181 |  |  |
| | | from | 181 | | |
Abstract
Based on Hydroxyethyl cellulose (HEC) and Acrylic acid (AAc), a series of biodegradable pH-sensitive hydrogels were prepared using gamma radiation as asuper clean source for polymerization and crosslinking. Incorporation of PAAc in the prepared hydrogel was confirmed by Fourier transform infrared spectroscopy (FTIR). Swelling data showed that the prepared hydrogels possessed pronounced pH sensitivity. In vitro release studies were performed to evaluate the hydrogel potential as a drug carrier using furosemide as a model drug. Experimental data showed that the release profile depends on both hydrogel composition and pH of the releasing medium