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العنوان
Validation of a prognostic score to predict short-term mortality in patients with acute-on-chronic liver failure /
الناشر
Mahmoud Sherbiny Ahmed Sherbiny ,
المؤلف
Mahmoud Sherbiny Ahmed Sherbiny
هيئة الاعداد
باحث / Mahmoud Sherbiny Ahmed Sherbiny
مشرف / Rabab Fouad Emam Omar
مشرف / Ahmed Aly Elray
مشرف / Hesham Ibrahim Elmakhzangy
تاريخ النشر
2018
عدد الصفحات
147 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأمراض المعدية
تاريخ الإجازة
7/5/2019
مكان الإجازة
جامعة القاهرة - كلية الطب - Tropical Medicine
الفهرس
Only 14 pages are availabe for public view

from 168

from 168

Abstract

Back ground: Acute-on-chronic liver failure (ACLF) is a syndrome characterized by acute decompensation (AD) of cirrhosis, organ/system failure(s) and high short-term mortality. Objectives: To assess cirrhotic patients hospitalized for an AD for the diagnosis and grading of ACLF and to predict short-term prognosis according to EASL-CLIF consortium to guide therapeutic decision. Patients and methods: 120 cirrhotic patients with AD were prospectively included. The patients were divided into ACLF and no ACLF patients according to EASL-CLIF Definition of ACLF. All patients followed up for 3 months from inclusion or mortality whichever was earlier. The Prognostic scores like CLIF-SOFA, CLIF-C OF, MELD, MELD-Na and child-pugh scores were evaluated for their ability to predict 28-d and 90-d mortality in all patients and patients with ACLF using AUROC. The CLIF»C AD score was evaluated for AD without ACLF