الفهرس 
Title : Effect of ketorolac premedicationon anesthetic efficiency of inferior alveolar nerve block, pre-treatment and post-endodontic pain in teeth with
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Abstract
Aim: It wasto assess effect of ketorolac premedication on the effectiveness of the inferior alveolar nerve block, pretreatment and postoperative pain in patients with symptomatic irreversible pulpitis. Methods: Thirty{u2013}eight patients, aged 18-45 years with no gender predilection, diagnosed with symptomatic irreversible pulpitis in their mandibular molars, were included. Each patient had a vital mandibular molar, was actively experiencing moderate tosevere pain, and had a prolonged response to cold testing with ethyl chloride spray. Patients were randomly assigned into either of these two groups: Ketorolac (experimental) group received pre-operative administration of 10 mg tablet of ketorolac, placebo (control) group received a placebo tablet that is similar to the ketorolac tablet one hour before endodontic treatment After 60 min of receiving premedication, the patient received a 1.8 ml standard IANBwith2% mepivacaine containing 1:100, 000epinephrine. The tooth in question was checked after 15 min for lip numbness and was tested with cold spray test and the patient was asked to rate his/her pain on NRS.Access cavity was performed.Patients were instructed to rate any pain felt during cold testing andendodontic procedure. When the patient felt pain, the treatment was immediately stopped, and the patient was asked to rate his/ her discomfort using NRS.The pain felt was recorded during access cavity preparation or instrumentation.The success of the IANB was defined as the ability to access and instrument the tooth with no or mild pain